Eleven-year-old Annie has been living in an orphanage her whole life run by cruel Miss Hannigan. After unsuccessful escape attempts, Grace Farrell comes to take the child home to live two weeks with billionaire Oliver Warbucks during Christmas. The plucky orphan worms her way into the hearts of the staff and Mr. Warbucks and even the President of the United States! But even though Mr. Warbucks wants to adopt her, she is still looking for her real parents who left a locket with her when they dropped her off at the orphanage.
- Kathy Bates - Miss Agatha Hannigan
- Victor Garber - Oliver Warbucks
- Alan Cumming - Daniel Francis "Rooster" Hannigan
- Audra McDonald - Grace Farrell
- Kristin Chenoweth - Lily St. Regis
- Alicia Morton - Annie Bennett
- Dennis Howard - F.D.R.